60Co-gamma ray can injure the chromesomes of bone marrow cells
and this injury may be measured by determining the rate of micronuclei of bone marrow cells of irradiated mice. Our observations indicated that the formation rate of micronuclei of bone marrow cells could decrease 472% if the mice had administered DNA from carp spermary (100 mg/kg weight) for 15 days before they were irradiated. Ultroviolet can damage DNA of cells. The damaged DNA can be repaired by the repair enzymes system in cells. The repairing speed can be measured by 3H-TdR intercalation (ie unscheduled DNA synthesis measurement
UDS measurement ). The results showed that the UDS of whole blood cells in mice had increased 4002% after DNA from carp spermary (30 mg/kg weight ) had been administered to the mice for 3 months.
关键词
&nbsp鲤鱼精巢脱氧核糖核酸微核率非程序DNA合成
Keywords
&nbspcarpspermarydeoxyribonucleic acid(DNA)rate of micronucleiunscheduled DNA synthesis(UDS)