The paper reported the establishment of a quantitative method for simultaneously determining four effective components in Compound Xueshuantong capsule by using one chemical reference

the new quality evaluation method

quantitative analysis of multicomponents by single marker(QAMS)

using Ginsenoside Rg

1

as the internal reference substance

was developed by HPLC to simultaneously determine Notoginsenoside R

1

Ginsenoside Rg

1

Ginsenoside Re

Ginsenoside Rb

1

in Compound Xueshuantong capsule with the relative correction factor (RCF). In addition

the results of QAMS method were validated by comparing with that of external standard method. The results show that the RCFs have good reproducibility and no significant differences between the quantitative results of QAMS method and external standard method were observed. So

it is a accurate

convenient and practical method to simultaneously determine four effective components in Compound Xueshuantong capsule for its quality control．