LI Panlin, HE Lili, LI Chuyuan, et al. Comparison of anti-inflammatory effects between Lonicerae Japonicae Flos and Lonicerae Flos using an acute stomatitis model[J]. Acta Scientiarum Naturalium Universitatis SunYatseni, 2016,55(4):118-122.
LI Panlin, HE Lili, LI Chuyuan, et al. Comparison of anti-inflammatory effects between Lonicerae Japonicae Flos and Lonicerae Flos using an acute stomatitis model[J]. Acta Scientiarum Naturalium Universitatis SunYatseni, 2016,55(4):118-122.DOI:
The acute stomatitis model in KB cells induced by cigarette smoke extract (CSE) has been established to study the anti-inflammatory effects between Lonicerae Japonicae Flos (LJF) and Lonicerae Flos (LF),and the protein expression levels of TNF-α
IL-6
IL-8 and IL-10 were detected by Elisa method after treatments of LJF or LF extracts. The results showed that the extracts of LJF or LF could both reduce the protein expression levels of TNF-α
IL-6
IL-8
improve the low expression of IL-10 in a dose dependent manner
suggesting their certain antiinflammatory effects.LF presented significant better antiinflammatory effects than LJF in the regulation of TNF-α
IL-6 and IL-10. These results provided a basis for the rational utilization of LJF and LF herbs.
关键词
金银花山银花KB细胞急性口腔炎症
Keywords
Lonicerae Japonicae FlosLonicerae FlosKB cellsacute stomatitis model