LIU Hong, ZHENG Yanfang, LI Chuyuan, et al. Protective effects of Kouyanqing Granule on the oral ulcer rat model with Yin-xu-huo-wang syndrome[J]. Acta Scientiarum Naturalium Universitatis SunYatseni, 2018,57(2):131-136.
LIU Hong, ZHENG Yanfang, LI Chuyuan, et al. Protective effects of Kouyanqing Granule on the oral ulcer rat model with Yin-xu-huo-wang syndrome[J]. Acta Scientiarum Naturalium Universitatis SunYatseni, 2018,57(2):131-136.DOI:
Kouyanqing Granule (KYQG) is a famous Chinese herbal formula for the treatment of oral diseases in clinic. Based on the Disease-syndrome theory of traditional Chinese medicine
the present study established an oral ulcer rat model with Yin-xu-huo-wang syndrome by the combination of 3
3′
5triiodothyronine injection and phenol burning. Through this rat model
KYQG's protective effects on reducing oral damage and promoting ulcer healing were evaluated including parameter detection and histopathological observation.