With unique geographical location， Qinling-Daba Mountain area has a fragile and sensitive ecological environment， and the population， resources， and environmental problems in the area have become increasingly prominent. The central Qinling-Daba Mountain area （Hanzhong， Ankang， and Shangluo） is studied to reveal the spatio-temporal evolution characteristics of ecological sensitivity and its influencing factors in the central Qinling-Daba Mountain area by using the data of DEM， land use， and population density of 2000， 2005， 2010， 2015， and 2018， and methods of PSR （pressure-state-response） model， entropy method， and geographical detector. The results show that： 1） the areas with high ecological sensitivity were mainly located in Hantai District， Luonan County， and Zhenping County， among them， Zhenping County was the most sensitive area in the study period. 2） The ecological sensitivity of the central Qinling-Daba Mountain area was in a downward trend， and the change of the most sensitive area was more significant， from 12.35% in 2000 to 2.91% in 2018. 3） By comparing the three cities， we found that in Hanzhong， the

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value of the population density of pressure index， the elevation of state index， and the maximum patch index of forest land of response index were large， forming the main effects on ecological sensitivity； in Ankang， the distance from the water was the dominant factor of the pressure index， the main driving factor of the state index was elevation， and the main influencing factor of response index was the degree of fragmentation of cultivated land； in Shangluo， the

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value of the population density of pressure index， the elevation of state index and the maximum patch index of forest land of response index were large and predominant. The results have significance for ecological planning and sustainable development in the central Qinling-Daba Mountain area.