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-N） and their influencing factors in different irrigation areas of the Manas river basin， six irrigation districts were selected as the research objects in May， August and October， 2019. The factors such as soil ammonium nitrogen and nitrate nitrogen， physical and chemical properties， soil environment， nitrogen application rate and development period were analyzed. The results showed that： （1） the differences of soil factors in various irrigation areas made the contents of ammonium nitrogen and nitrate nitrogen significantly changed in descending degree from Xiayedi irrigation area， Mosuowan irrigation area， Anjihai irrigation area， Xinhu general field irrigation area，and Jingouhe irrigation area to Shihezi irrigation area. The ammonium nitrogen and nitrate nitrogen showed obvious seasonal variations， with the change of nitrate nitrogen in descending order in August，October and May.Ammonium nitrogen and nitrate nitrogen accumulated in the surface layer of soil in different months， and decreased with the increase of soil depth. （2） Ammonium nitrogen was negatively correlated with pH， positively correlated with total salt， and positively correlated with water content in May and August； nitrate nitrogen content was positively correlated with soil water content and total salt， and negatively correlated with soil temperature. （3） Soil pH， temperature， total salt and soil water content are the main factors affecting the content of ammonium nitrogen and nitrate nitrogen， while the duration of farmland development and nitrogen application rate have indirect impact on ammonium nitrogen and nitrate nitrogen content.