In order to search for the novel secondary metabolites from marine microorganisms

Penicillium

sp.  GGF16-1-2 which was isolated from China starfish

was carried out by opening column chromatography

HPLC

etc. Seven known compounds were obtained from the EtOAc layer of broth of

Penicillium

sp.  GGF16-1-2. Their structures were identified by physical data

spectroscopic analysis and comparing with the references

and these compounds were named as dicitrinones (1)

microsphaeropsones (2)

janthinone (3)

microxanthone (4)

emodin (5)

8-hydroxy-6-methylxanthone-1-carboxylic acid (6) and coniochaetone (7). Compounds 2

4 and 6 were isolated from the genus

Penicillium

for the first time.