Heavy metal pollution is an important factor in affecting rice growth and quality of rice. Among all kinds of heavy metal pollution

the cadmium pollution is the most serious one. It is not very clear about the mechanisms of rice responding to cadmium and the measures dealing with pollution. In this paper

to investigate the molecular mechanism of rice response to the Cd treatment (05 mM) and to search for rice genes associated with these mechanisms

suppression subtractive hybridization and mirror orientation selection were conducted to construct cDNA libraries with Cd and nonCd treatment rice (Oryza sativa L.

Nipponbare) seedling roots

and cDNA microarray for these two materials was conducted. The results of this study will help to clarify the molecular mechanisms of rice responding cadmium stress

and provide a way of isolating genes involved in heavymetal resistance in rice.