Fungus 

Aspergillus

 sp.

which was isolated from soft coral Sarcophyton tortuosum

 could produce mycotoxin penicillic acid with the yield of 55 mg/L in GPY medium containing glucose 10 g/L

peptone 5 g/L

yeast extract 2 g/L

sea water 1 L

at pH 7.5 Interestingly

while the GPY medium supplied with αpinene at a dose of 200 mg/L

the constitute and content of the metabolites of Aspergillus sp altered obviously Furthermore

the yield of penicillic acid in the culture broth increased dramatically from 5.5 mg/L in control group (GPY medium) to 29.15 mg/L in biotransformation group Based on the gas chromatography mass spectrometry analysis

the major biotransformed products of αpinene were characterized as oxygenated monoterpenoids

which were undergone further biodegradation This finding suggested that monoterpene substrate

αpinene could used to be an elicitor It can alter the oxidase activities

trigger and modulate microbial metabolic pathways

and has potential application in fermentation