Reinvestigation on the Secondary Metabolites of Marine Fungus Penicillium sp.from the South China Sea

WEI Meiyan; SHAO Changlun; ; TAN Ni; HU Guping; WANG Changyun; SHE Zhigang; LIN Yongcheng

您当前的位置：

首页 >

文章列表页 >

Reinvestigation on the Secondary Metabolites of Marine Fungus Penicillium sp.from the South China Sea

更新时间：2023-12-11

- Reinvestigation on the Secondary Metabolites of Marine Fungus Penicillium sp.from the South China Sea
- Acta Scientiarum Naturalium Universitatis SunYatseni Vol. 49, Issue 4, Pages: 77-80(2010)
- 作者机构：
  
  1. 中国海洋大学医药学院，山东青岛 266003
  2. 中山大学化学与化学工程学院，广东广州 510275
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2010，
  
  Published Online：25 July 2010，
扫描看全文
WEI Meiyan, SHAO Changlun, , et al. Reinvestigation on the Secondary Metabolites of Marine Fungus Penicillium sp.from the South China Sea. [J]. Acta Scientiarum Naturalium Universitatis SunYatseni 49(4):77-80(2010)
DOI：

WEI Meiyan, SHAO Changlun, , et al. Reinvestigation on the Secondary Metabolites of Marine Fungus Penicillium sp.from the South China Sea. [J]. Acta Scientiarum Naturalium Universitatis SunYatseni 49(4):77-80(2010) DOI：

摘要

重新研究南海海洋真菌Penicillium sp. 386的次级代谢产物，运用硅胶柱层析、制备薄层层析和重结晶等方法，从中分离鉴定了9个单体化合物，包括3个神经酰胺类化合物 (1，2，3)，3个环二肽类化合物 (4，5，6)，2个甾醇类 (7，8)和1个结构新颖的生物碱化合物 (9)。其中化合物1个结构是通过乙酰化，水解等化学方法以及NMR、GC-MS等技术得以确定。化合物9的结构主要通过波谱方法得以确定的，尤其是2D NMR，最后有单晶X射线测定得以证实。

Abstract

The secondary metabolites of the marine fungus Penicillium sp. from the South China Sea was investigated using silica get column chromatography

preparative thinlayer chromatography and recrystallization

resulting in isolation of nine pure compounds

including three ceramides (1

three cyclodipeptides (4

two sterols (7

8) and one structurally unique alkaloid (9).The structure of 1 was characterized by acetylation

hydrolysis reaction

NMR and GCMS and the structure of 9 was analyzed by comprehensive spectroscopic methods

2D NMR

and Xray analysis.

关键词

海洋真菌Penicillium sp.神经酰胺化学反应penicillazineX射线结构鉴定

Keywords

references

Views

136

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

长纹海鞘(Ascidia longistriara)的化学成分研究

A Principle of Element Dilution(Ⅰ)

苦皮藤中两个倍半萜多酯

尾叶香茶菜中对映-贝壳杉烯型二萜

Ceramide from the Marine Sponge Phyllospongia sp

Related Author

王艳红

闫素君

苏镜娱

曾陇梅

Jianfong

Chen Ziang Hong

Zhong Guangtao

杨立

Related Institution

中山大学化学与化学工程学院

届毕业生

中山大学化学系 80届毕业生

中山大学化学系

兰州大学应用有机国家重点实验室

Postal code：510275
Tel：020-84112585，84113223 Email：xuebaozr@mail.sysu.edu.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰