The Metabolites of the Marine Fungus  Penicillium  sp. Associated with Soft Coral Sarcophyton tortuosum

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The Metabolites of the Marine Fungus Penicillium sp. Associated with Soft Coral Sarcophyton tortuosum

更新时间：2023-12-11

- The Metabolites of the Marine Fungus Penicillium sp. Associated with Soft Coral Sarcophyton tortuosum
- Acta Scientiarum Naturalium Universitatis SunYatseni Vol. 50, Issue 6, Pages: 72-77(2011)
- 作者机构：
  
  1. 中山大学药学院,广东,广州,510006
  2. 
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2011，
  
  Published Online：25 November 2011，
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The Metabolites of the Marine Fungus Penicillium sp. Associated with Soft Coral Sarcophyton tortuosum. [J]. Acta Scientiarum Naturalium Universitatis SunYatseni 50(6):72-77(2011)
DOI：

The Metabolites of the Marine Fungus Penicillium sp. Associated with Soft Coral Sarcophyton tortuosum. [J]. Acta Scientiarum Naturalium Universitatis SunYatseni 50(6):72-77(2011) DOI：

摘要

从三亚采集的软珊瑚Sarcophyton tortuosum体内分离得到一株共生真菌Penicillium sp.，该菌在GPY培养基中培养，菌体呈浅红色。对该菌菌体的代谢产物进行了研究，纯化得到1个新化合物：(4E

6E)-2-N-十六碳酰基-1

3-二羟基十六烷-4

6-二烯-鞘胺醇 (1)，以及4个已知化合物1

7-二羟基-3-甲氧基-6-甲基-蒽醌（2），1

8-三羟基-3-甲氧基-6-甲基-蒽醌（3），1-羟基-3-甲氧基-6-甲基-蒽醌（4），4

8-二甲基-1

5-二氧环辛烷-2

6-二酮（5）。化合物结构主要通过MS，NMR等波谱数据分析确定。化合物2，3，4，5〖STBZ〗为首次从海洋真菌中分离得到。

Abstract

Marine fungus Penicillium sp. was isolated from the soft coral Sarcophyton tortuosum collected in the South China Sea. While cultured in GPY medium

the fungal mycelia were reddish. Five compounds including (4E

6E) 2-N-hexadecanoyl-1

3-dihydroxyhexadeca-4

6-dien sphingosine(1)

7-dihydroxy-3-methoxy-6-methyl -anthraquinone macrosporin (2)

8- trihydroxy- 3- methoxy-6-methyl- anthraquinone (3)

1-hydroxy-3-methoxy-6-methyl-anthraquinone (4) and 4

8- dimethyl-1

5-dioxocane-2

6-dione (5)were obtained from the methanol extract of the fungal mycelia. Their structures were characterized by MS and NMR analyses. The result indicated that the compound (1) was a new compound

and the compounds 2，3，4，5 were first isolated from the marine fungus.

关键词

海洋真菌Penicillium sp.(4E6E)-2-N-十六碳酰基-13-二羟基十六烷-46-二烯-鞘胺醇蒽醌

Keywords

marine fungusPenicillium sp.(4E6E)2-N-Hexadecanoyl-13- dihydroxyhexadeca- 46-dien sphingosineanthraquinone

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