The study was aiming for the Pharmacodynamic of Gangmei Ganmaoling granule fluid extract. By using pharmacological model

the toxicity

and antiinflammatory in mice

the antipyretic in rat

and analgesic effects of Gangmei Ganmaoling granule fluid extract were tested. The results showed that Gangmei Ganmaoling granule fluid extract has a low of toxicity . It can suppress the body temperature induced by 2

4-dinitrophenol in rats. The inflammatory swelling induced by xylene in ear of mice was alleviated. The capillary permeability induced by glacial acetic acid in mice was restrained. Analgesic study showed that the pain threshold of temperature stimuli was increased markedly in mice

the writhe incubation period was prolonged

and the number of writhe induced by abdominal of glacial acetic acid were decreased. In conclusion Gangmei Ganmaoling granule fluid extract was of low toxicity

with antipyretic

anti-flammatory and analgesic effects

which proved to be a safe and effective compound preparation of traditional Chinese medicine.