The thermal decomposition of sucralose was measured using TG-DSC-FTIR hyphenated techniques under air flow and nitrogen flow. The result shows that the thermal process contains four stages. The first stage is endothermic

and the others are exothermic. The fourth stage has different reaction mechanism between under air flow and under nitrogen flow. FTIR analysis indicates that degradation of sucrolose cooked at high temperature does not produce poisonous material.