The study is to optimize and establish the extraction process of the Chinese herbal Compound BaoXieNing used for Antidiarrhea in Infant. The process was optimized by taking the extraction percentages of evodiamine

rutaecarpine

eugenol

cinnamic aldehyde as the evaluation parameters

considering the concentration of ethanol (extraction solvent)

liquidsolid ratio

extraction time

extraction times as the affecting factor

and the extraction process of BXN optimized by L

9

(3

4

) orthogonal design. The results show that optimum condition is achieved when the concentration of ethanol is 95%

liquid-solid ratio is 10 (V/m)

 the mixed herbs are extracted twice while 2 hours for each time. The established optimum extraction process is efficient for the extraction of BXN

and is a stable

economical and convenient method.